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NASC Stock Detail Page

NASC ID: N6954

Name: Dicer-like 4

ABRC stock number: CS6954

Description: DCL4 is a component of the SGS3/RDR6 pathway and acts downstream of RDR6. dcl4-2 affects a glutamic acid that is completely conserved in Dicers from Arabidopsis (At), Homo sapiens (Hs), C. elegans (Ce), Drosophila melanogaster (Dm), and S. pombe (Sp). dcl4-2 interferes with the biogenesis of siR1511 and siR255 but does not affect miR173.

Donation Date: 2007-09-19

Donated by:  University of Pennsylvania Scott Poethig

Donor Number: dcl4-2

Part of : Homozygous lines

Stock type: individual line

Material type: seed

Comment: recessive

Status Price (£)
Currently unavailable £7.50

Germplasm Info

Seed type: Mutant

Mutagen: ethylmethane sulfonate

Background: Col(Columbia)

Segregation status: homozygous

Associated Polymorphisms

When available, select a locus to display it at the AIP or view the EMBL record at the EBI.

Allele: Locus: AGI code:
  • dcl4-2
  • DCL4


Leaves elongated and curled downwards; produces abaxial trichomes precociously. Morphological phenotype similar to zip, rdr6 and sgs3. Blocks silencing of L1 transgene.


Yoshikawa, M. et al. 2005. A pathway for the biogenesis of trans-acting siRNAs in Arabidopsis. Genes & Development 19(18):2164-75.PubMed ID: 16131612.