NASC Stock Detail Page
NASC ID: N6954
Name: Dicer-like 4
ABRC stock number: CS6954
Description: DCL4 is a component of the SGS3/RDR6 pathway and acts downstream of RDR6. dcl4-2 affects a glutamic acid that is completely conserved in Dicers from Arabidopsis (At), Homo sapiens (Hs), C. elegans (Ce), Drosophila melanogaster (Dm), and S. pombe (Sp). dcl4-2 interferes with the biogenesis of siR1511 and siR255 but does not affect miR173.
Donation Date: 2007-09-19
| Donated by: | University of Pennsylvania Scott Poethig |
Donor Number: dcl4-2
Part of : Homozygous lines
Stock type: individual line
Material type: seed
Comment: recessive
| Status | Price (£) |
|---|---|
| Currently unavailable | £11.00 |
Germplasm Info
Seed type: Mutant
Mutagen: ethylmethane sulfonate
Background: Col(Columbia)
Segregation status: homozygous
Associated Polymorphisms
When available, select a locus to display it at the AIP or view the EMBL record at the EBI.
| Gene: | Allele: | Locus: | AGI code: |
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Phenotype
Leaves elongated and curled downwards; produces abaxial trichomes precociously. Morphological phenotype similar to zip, rdr6 and sgs3. Blocks silencing of L1 transgene.
References
Yoshikawa, M. et al. 2005. A pathway for the biogenesis of trans-acting siRNAs in Arabidopsis. Genes & Development 19(18):2164-75.PubMed ID: 16131612.