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NASC Stock Detail Page

NASC ID: N9857

Name: jag-1

ABRC stock number: CS9857

Description: pSKI015 insertion. Arabidopsis Knockout Facility at the University of Wisconsin-Madison

Donation Date: 2008-06-02

Donated by:  Max-Planck-Institute for Developmental Biology Detlef Weigel

Donor Number: jag-1

Part of : Homozygous lines

Stock type: individual line

Material type: seed

Comment: related stock in background Ws-2: N9505

Status Price (£)
Available £7.50

Germplasm Info

Mutagen: T-DNA Insertion

Background: Col-0

Segregation status: homozygous

Associated Polymorphisms

When available, select a locus to display it at the AIP or view the EMBL record at the EBI.

Allele: Locus: AGI code:
  • jag-1
  • jag

Phenotype

Loss of JAGGED function causes organs to have serrated margins. In leaves, the blade region is most severely affected. In sepals, petals and stamens, the strongest defects are seen in the distal regions. By monitoring cell-cycle activity in developing petals with the expression of HISTONE 4, we show that JAGGED suppresses the premature differentiation of tissues, which is necessary for the formation of the distal region. The localization of defects overlaps with the expression domain of JAGGED, which is restricted to the growing regions of lateral organs.

References

Dinneny, J.R. et al. 2004. The role of JAGGED in shaping lateral organs. Development 131(5):1101-10.PubMed ID: 14973282.

Dinneny, J.R., Weigel, D. & Yanofsky, M.F. 2006. NUBBIN and JAGGED define stamen and carpel shape in Arabidopsis. Development 133(9):1645-55.PubMed ID: 16554365.